Cldn18^{tm1(cre/ERT2)Cya}
Targeted Allele Detail

Summary

• Symbol: Cldn18^{tm1(cre/ERT2)Cya}
• Name: claudin 18; targeted mutation 1, Cyagen Biosciences
• MGI ID: MGI:7657228
• Synonyms: Cldn18^{tm1(IRES-CreERT2)}
• Gene: Cldn18 Location: Chr9:99572849-99599320 bp, - strand Genetic Position: Chr9, 52.0 cM, cytoband E3-F1
• Alliance: Cldn18^{tm1(cre/ERT2)Cya} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:326541
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Targeted (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Cldn18^{tm1(cre/ERT2)Cya} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Cldn18 (MGI:1929209)

• The IRES-CreERT2 cassette was inserted ~60~100bp downstream of the TGA stop codon. (J:326541)
• Inheritance: Not Specified

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Cldn18 (mouse) Summary of all recombinase alleles driven by Cldn18. Alliance mouse Cldn18 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cldn18 Mutation: 19 strains or lines available

References

• Original: J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022
• All: 1 reference(s)