Sftpc^{em2(cre/Esr1*)Cya}
Endonuclease-mediated Allele Detail

Summary

• Symbol: Sftpc^{em2(cre/Esr1*)Cya}
• Name: surfactant associated protein C; endonuclease-mediated mutation 2, Cyagen Biosciences
• MGI ID: MGI:7657324
• Synonyms: Sftpc^{em2(IRES-MerCreMer)}
• Gene: Sftpc Location: Chr14:70758389-70761521 bp, - strand Genetic Position: Chr14, 36.32 cM
• Alliance: Sftpc^{em2(cre/Esr1*)Cya} page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Sftpc^{em2(cre/Esr1*)Cya} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Sftpc (MGI:109517)

• Mutation details: The IRES-MerCreMer cassette was inserted into the 3UTR (exon 6). Using IRES as a linker to achieve co-expression. (J:326541)
• Inheritance: Not Specified

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Sftpc (mouse) Summary of all recombinase alleles driven by Sftpc. Alliance mouse Sftpc gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Sftpc Mutation: 24 strains or lines available

References

• Original: J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022
• All: 1 reference(s)