Slc22a18^tm1Tgot
Targeted Allele Detail

Summary

• Symbol: Slc22a18^tm1Tgot
• Name: solute carrier family 22 (organic cation transporter), member 18; targeted mutation 1, Takanari Gotoda
• MGI ID: MGI:7657433
• Gene: Slc22a18 Location: Chr7:143027502-143053071 bp, + strand Genetic Position: Chr7, 88.22 cM
• Alliance: Slc22a18^tm1Tgot page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:349247
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• A loxP and FRT flanked neomycin selection cassette replaced exons 2-5. (J:349247)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Slc22a18 Mutation: 21 strains or lines available

References

• Original: J:349247 Yamamoto T, et al., Overexpression of Slc22a18 facilitates fat accumulation in mice. Biochem Biophys Res Commun. 2024 Jun 18;712-713:149922
• All: 1 reference(s)