Tg(Fabp2-Slc22a18)#Tgot
Transgene Detail

Summary

• Symbol: Tg(Fabp2-Slc22a18)#Tgot
• Name: transgene insertion, Takanari Gotoda
• MGI ID: MGI:7657446
• Synonyms: aP2-rSlc22a18 Tg
• Transgene: Tg(Fabp2-Slc22a18)#Tgot Location: unknown
• Alliance: Tg(Fabp2-Slc22a18)#Tgot page

Transgene origin

• Strain of Origin: C57BL/6J

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Fabp2-Slc22a18)#Tgot expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  rat

  Slc22a18 (309131)

  Slc22a18

  (MGI:1336884)

• Tg(Fabp2-Slc22a18)#Tgot expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Fabp2 (MGI:95478)

• Mutation details: The entire coding region of rat Slc22a18 is under the control of the adipose-specific fatty acid-binding protein 4 enhancer/promoter region. Western blot analysis confirmed expression in epididymal fat. Three lines were generated: 002, 006, and 019. This record represents pooled data or data where the line number is not specified. (J:349247)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:349247 Yamamoto T, et al., Overexpression of Slc22a18 facilitates fat accumulation in mice. Biochem Biophys Res Commun. 2024 Jun 18;712-713:149922
• All: 1 reference(s)