Urb1^em1Jil
Endonuclease-mediated Allele Detail

Summary

• Symbol: Urb1^em1Jil
• Name: URB1 ribosome biogenesis 1 homolog (S. cerevisiae); endonuclease-mediated mutation 1, Jinsong Li
• MGI ID: MGI:7660773
• Gene: Urb1 Location: Chr16:90548415-90607301 bp, - strand Genetic Position: Chr16, 51.92 cM, cytoband C3.3
• Alliance: Urb1^em1Jil page

Mutation origin

• Strain of Origin: B6D2F1

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Insertion
• CRISPR-targeting resulted in a 2 bp insertion and frameshift mutation. (J:344930)
• Inheritance: Not Specified

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Urb1 Mutation: 107 strains or lines available

References

• Original: J:344930 Shan L, et al., Nucleolar URB1 ensures 3' ETS rRNA removal to prevent exosome surveillance. Nature. 2023 Mar;615(7952):526-534
• All: 1 reference(s)