Naalad2^em1Jzhan
Endonuclease-mediated Allele Detail

Summary

• Symbol: Naalad2^em1Jzhan
• Name: N-acetylated alpha-linked acidic dipeptidase 2; endonuclease-mediated mutation 1, Jing Zhang
• MGI ID: MGI:7662575
• Gene: Naalad2 Location: Chr9:18233247-18308834 bp, - strand Genetic Position: Chr9, 7.02 cM, cytoband A3
• Alliance: Naalad2^em1Jzhan page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR/cas9 mediated recombination using guide RNAs targeting exons 3-5 created a null allele. (J:344894)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Naalad2 Mutation: 45 strains or lines available

References

• Original: J:344894 Ji T, et al., Deletion of glutamate carboxypeptidase II (GCPII), but not GCPIII, provided long-term benefits in mice with traumatic brain injury. CNS Neurosci Ther. 2023 Dec;29(12):3786-3801
• All: 1 reference(s)