Zfp280c^em1Xss
Endonuclease-mediated Allele Detail

Summary

• Symbol: Zfp280c^em1Xss
• Name: zinc finger protein 280C; endonuclease-mediated mutation 1, Xing-sheng Shu
• MGI ID: MGI:7662826
• Gene: Zfp280c Location: ChrX:47630502-47683381 bp, - strand Genetic Position: ChrX, 25.68 cM
• Alliance: Zfp280c^em1Xss page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR/Cas9 technology deleted exons 3 to 19. (J:331404)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Zfp280c Mutation: 10 strains or lines available

References

• Original: J:331404 Ying Y, et al., Zinc finger protein 280C contributes to colorectal tumorigenesis by maintaining epigenetic repression at H3K27me3-marked loci. Proc Natl Acad Sci U S A. 2022 May 31;119(22):e2120633119
• All: 1 reference(s)