Frmd3^em1Zhaj
Endonuclease-mediated Allele Detail

Summary

• Symbol: Frmd3^em1Zhaj
• Name: FERM domain containing 3; endonuclease-mediated mutation 1, Jun Zhan
• MGI ID: MGI:7664563
• Gene: Frmd3 Location: Chr4:73931679-74120451 bp, + strand Genetic Position: Chr4, 36.06 cM
• Alliance: Frmd3^em1Zhaj page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Not Specified
• CRISPR/Cas9 technology generated a knock-out allele. (J:350496)

Disease models

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Tumor Data

List all tumor models in MMHCdb carrying Frmd3^em1Zhaj

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Frmd3 Mutation: 35 strains or lines available

References

• Original: J:350496 Ma J, et al., Tumor suppressor FRMD3 controls mammary epithelial cell fate determination via notch signaling pathway. Sci Adv. 2024 Jul 5;10(27):eadk8958
• All: 1 reference(s)