Thap4^em1Nvl
Endonuclease-mediated Allele Detail

Summary

• Symbol: Thap4^em1Nvl
• Name: THAP domain containing 4; endonuclease-mediated mutation 1, Nippon Veterinary and Life Science University
• MGI ID: MGI:7665254
• Gene: Thap4 Location: Chr1:93633113-93682560 bp, - strand Genetic Position: Chr1, 47.29 cM, cytoband D
• Alliance: Thap4^em1Nvl page

Mutation origin

• Strain of Origin: C57BL/6JJcl

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR/Cas9 technology generated a 2454 bp deletion that includes exon 2. (J:350810)

Expression

In Structures Affected by this Mutation:

5 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Thap4 Mutation: 23 strains or lines available

References

• Original: J:350810 Katayama K, et al., Mutation of the Thap4 gene causes dwarfism and testicular anomalies in rats and mice. Mamm Genome. 2024 Jun;35(2):149-159
• All: 1 reference(s)