Garin5b^em1Osb
Endonuclease-mediated Allele Detail

Summary

• Symbol: Garin5b^em1Osb
• Name: golgi associated RAB2 interactor family member 5B; endonuclease-mediated mutation 1, Research Institute for Microbial Diseases, Osaka University
• MGI ID: MGI:7666155
• Gene: Garin5b Location: Chr7:4756225-4774301 bp, - strand Genetic Position: Chr7, 2.75 cM
• Alliance: Garin5b^em1Osb page

Mutation origin

• Strain of Origin: (C57BL/6 x DBA/2)F2

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR/Cas9 technology generated a 13,436 bp deletion encompassing exons 1 to 9. (J:350937)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Garin5b Mutation: 37 strains or lines available

References

• Original: J:350937 Wang H, et al., Golgi associated RAB2 interactor protein family contributes to murine male fertility to various extents by assuring correct morphogenesis of sperm heads. PLoS Genet. 2024 Jun;20(6):e1011337
• All: 1 reference(s)