Rps27^{em2(Rps27l)Mbar}
Endonuclease-mediated Allele Detail

Summary

• Symbol: Rps27^{em2(Rps27l)Mbar}
• Name: ribosomal protein S27; endonuclease-mediated mutation 2, Maria Barna
• MGI ID: MGI:7703430
• Gene: Rps27 Location: Chr3:90119974-90120955 bp, - strand Genetic Position: Chr3, 39.21 cM
• Alliance: Rps27^{em2(Rps27l)Mbar} page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Inserted expressed sequence, Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Rps27^{em2(Rps27l)Mbar} expresses 1 gene
  Knock-in expresses:
  

  Organism	Expressed Gene	Note
  mouse	Rps27l (MGI:1915191)

• Mutation details: CRISPR/cas9-mediated recombination using guide RNAs replaced exon 2 with exon 2 from mouse Rps27l which differs by 3 residues from the exon of Rps27. (J:351545)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rps27 Mutation: 6 strains or lines available

References

• Original: J:351545 Xu AF, et al., Subfunctionalized expression drives evolutionary retention of ribosomal protein paralogs Rps27 and Rps27l in vertebrates. Elife. 2023 Jun 12;12
• All: 1 reference(s)