Runx1t1tm1c(EUCOMM)Hmgu
Targeted Allele Detail
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Symbol: |
Runx1t1tm1c(EUCOMM)Hmgu |
Name: |
RUNX1 translocation partner 1; targeted mutation 1c, Helmholtz Zentrum Muenchen GmbH |
MGI ID: |
MGI:7703692 |
Gene: |
Runx1t1 Location: Chr4:13743436-13893649 bp, + strand Genetic Position: Chr4, 5.88 cM, cytoband A
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Alliance: |
Runx1t1tm1c(EUCOMM)Hmgu page
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IMPC: |
Runx1t1 gene page |
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Mutant Cell Line: |
HEPD0697_3_E08 |
Germline Transmission: |
Earliest citation of germline transmission:
J:157065
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Parent Cell Line: |
JM8A3.N1 (ES Cell)
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Strain of Origin: |
C57BL/6N-Atm1Brd
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Project Collection: |
EUCOMM
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Allele Type: |
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Targeted (Conditional ready, No functional change) |
Mutation: |
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Insertion
Vector: L1L2_Bact_P
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Mutation details: The L1L2_Bact_P cassette was inserted at position 13837241 of Chromosome 4 upstream of the critical exon(s) (Build GRCm39). The cassette is composed of an FRT flanked lacZ/neomycin sequence followed by a loxP site. An additional loxP site is inserted downstream of the targeted exon(s) at position 13838345. The critical exon(s) is/are thus flanked by loxP sites. A "conditional ready" (floxed) allele was created by flp recombinase expression in mice carrying this allele to remove the lacZ sequence and neo selection cassette, leaving loxP sites flanking the critical exon(s). Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml
(J:157065)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Runx1t1 Mutation: |
37 strains or lines available
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Original: |
J:157065 Helmholtz Zentrum Muenchen GmbH, Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu). MGI Direct Data Submission. 2010-2015; |
All: |
1 reference(s) |
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