Slitrk4^tm1.1Jaru
Targeted Allele Detail

Summary

• Symbol: Slitrk4^tm1.1Jaru
• Name: SLIT and NTRK-like family, member 4; targeted mutation 1.1, Jun Aruga
• MGI ID: MGI:7703964
• Gene: Slitrk4 Location: ChrX:63308491-63320602 bp, - strand Genetic Position: ChrX, 34.57 cM, cytoband A5
• Alliance: Slitrk4^tm1.1Jaru page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:348363
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The open reading frame was replaced with a floxed neo cassette via homologous recombination. Cre mediated recombination removed the neo cassette. (J:348363)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Slitrk4 Mutation: 9 strains or lines available

References

• Original: J:348363 Matsumoto Y, et al., Slitrk4 is required for the development of inhibitory neurons in the fear memory circuit of the lateral amygdala. Front Mol Neurosci. 2024;17:1386924
• All: 1 reference(s)