Slc17a3^em1Araka
Endonuclease-mediated Allele Detail

Summary

• Symbol: Slc17a3^em1Araka
• Name: solute carrier family 17 (sodium phosphate), member 3; endonuclease-mediated mutation 1, Hiroshi Arakawa
• MGI ID: MGI:7704013
• Synonyms: Npt4^-
• Gene: Slc17a3 Location: Chr13:24023417-24044699 bp, + strand Genetic Position: Chr13, 9.95 cM
• Alliance: Slc17a3^em1Araka page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: CRISPR/Cas9 technology generated a 267 bp deletion that deleted exon 7, resulting in frameshift-mediated nonsense-mediated mRNA decay. (J:351593)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Slc17a3 Mutation: 49 strains or lines available

References

• Original: J:351593 Imamura R, et al., Role of Organic Anion Transporter NPT4 in Renal Handling of Uremic Toxin 3-indoxyl Sulfate. J Pharm Sci. 2024 Jul;113(7):1996-2000
• All: 1 reference(s)