Slmap^tm1.1Tuab
Targeted Allele Detail

Summary

• Symbol: Slmap^tm1.1Tuab
• Name: sarcolemma associated protein; targeted mutation 1, Balwant S Tuana
• MGI ID: MGI:7704162
• Synonyms: flox-SLMAP
• Gene: Slmap Location: Chr14:26134323-26256086 bp, - strand Genetic Position: Chr14, 16.09 cM, cytoband B
• Alliance: Slmap^tm1.1Tuab page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:350523
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, Modified isoform(s))
• Mutation: Insertion
• Mutation details: LoxP sites were inserted around exon 3 via homologous recombination. This targets the Slmap3 isoforms with a start sites in exons 2 or 3 while leaving intact Slmap1 and Slmap2 isoforms with start sites in exon 10 and exon 16, respectively. (J:350523)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Slmap Mutation: 68 strains or lines available

References

• Original: J:350523 Rehmani T, et al., Specific deletion of the FHA domain containing SLMAP3 isoform in postnatal myocardium has no impact on structure or function. Cardiogenetics. 2021;11:164-184
• All: 2 reference(s)