Zfp282^em1Bbw
Endonuclease-mediated Allele Detail

Summary

• Symbol: Zfp282^em1Bbw
• Name: zinc finger protein 282; endonuclease-mediated mutation 1, Binbin Wang
• MGI ID: MGI:7707397
• Gene: Zfp282 Location: Chr6:47854138-47885419 bp, + strand Genetic Position: Chr6, 22.94 cM
• Alliance: Zfp282^em1Bbw page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: CRISPR/Cas9 technology generated a 13,824 bp deletion containing exons 2 to 5. RT-PCR confirmed the absence of mRNA in testis. (J:352416)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Zfp282 Mutation: 34 strains or lines available

References

• Original: J:352416 Wei H, et al., A pathogenic AKAP4 variant, p.R429H, causes male in/subfertility in humans and mice. Clin Transl Med. 2023 Dec;13(12):e1463
• All: 1 reference(s)