Tecrl^em1Bcgen
Endonuclease-mediated Allele Detail

Summary

• Symbol: Tecrl^em1Bcgen
• Name: trans-2,3-enoyl-CoA reductase-like; Tecrl^em1Bcgen
• MGI ID: MGI:7707933
• Gene: Tecrl Location: Chr5:83425992-83503042 bp, - strand Genetic Position: Chr5, 43.0 cM
• Alliance: Tecrl^em1Bcgen page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR/Cas9 technology deleted exons 3-4. (J:325991)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tecrl Mutation: 34 strains or lines available

References

• Original: J:325991 Hou C, et al., TECRL deficiency results in aberrant mitochondrial function in cardiomyocytes. Commun Biol. 2022 May 16;5(1):470
• All: 1 reference(s)