Vamp4^em1Tax
Endonuclease-mediated Allele Detail

Summary

• Symbol: Vamp4^em1Tax
• Name: vesicle-associated membrane protein 4; endonuclease-mediated mutation 1, Tao Xu
• MGI ID: MGI:7708019
• Gene: Vamp4 Location: Chr1:162398084-162426651 bp, + strand Genetic Position: Chr1, 70.29 cM, cytoband H1
• Alliance: Vamp4^em1Tax page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR/cas9 mediated recombination using guide RNAs deleted exons 3 - 7. (J:352764)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Vamp4 Mutation: 17 strains or lines available

References

• Original: J:352764 Li M, et al., VAMP4 regulates insulin levels by targeting secretory granules to lysosomes. J Cell Biol. 2022 Oct 3;221(10)
• All: 1 reference(s)