Lrriq1^em1Ysato
Endonuclease-mediated Allele Detail

Summary

• Symbol: Lrriq1^em1Ysato
• Name: leucine-rich repeats and IQ motif containing 1; endonuclease-mediated mutation 1, Youichi Sato
• MGI ID: MGI:7711345
• Gene: Lrriq1 Location: Chr10:102881892-103072183 bp, - strand Genetic Position: Chr10, 53.65 cM, cytoband D1
• Alliance: Lrriq1^em1Ysato page

Mutation origin

• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Insertion
• Mutation details: CRISPR/Cas9 technology generated a 1-bp insertion (G) in the 18th amino acid which caused a frameshift in which amino acid 21 was substituted from lysine to a stop codon. (J:338085)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Lrriq1 Mutation: 92 strains or lines available

References

• Original: J:338085 Fukutomi M, et al., Lrriq1 is an essential factor for fertility by suppressing apoptosis. J Assist Reprod Genet. 2022 Nov;39(11):2647-2657
• All: 1 reference(s)