Gpr75^em1Tes
Endonuclease-mediated Allele Detail

Summary

• Symbol: Gpr75^em1Tes
• Name: G protein-coupled receptor 75; endonuclease-mediated mutation 1, Lino Tessarollo
• MGI ID: MGI:7711515
• Gene: Gpr75 Location: Chr11:30835358-30843729 bp, + strand Genetic Position: Chr11, 18.16 cM
• Alliance: Gpr75^em1Tes page

Mutation origin

• Strain of Origin: C57BL/6Ncr x (C57BL/6J x DBA/2J)F1

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR/Cas9 technology generated a 234 bp deletion. (J:338012)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gpr75 Mutation: 31 strains or lines available

References

• Original: J:338012 Speidell A, et al., Mice deficient for G-protein-coupled receptor 75 display altered presynaptic structural protein expression and disrupted fear conditioning recall. J Neurochem. 2023 Jun;165(6):827-841
• All: 1 reference(s)