Dst^em4Dcr
Endonuclease-mediated Allele Detail

Summary

• Symbol: Dst^em4Dcr
• Name: dystonin; endonuclease-mediated mutation 4, Derry C Roopenian
• MGI ID: MGI:7712933
• Gene: Dst Location: Chr1:33947306-34347742 bp, + strand Genetic Position: Chr1, 12.91 cM
• Alliance: Dst^em4Dcr page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Modified isoform(s))
• Mutation: Intragenic deletion
• This CRISPR/cas9-mediated mutation is a 51bp in-frame deletion in exon 23 (J:352178)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Dst Mutation: 557 strains or lines available

References

• Original: J:352178 Sproule TJ, et al., Dystonin modifiers of junctional epidermolysis bullosa and models of epidermolysis bullosa simplex without dystonia musculorum. PLoS One. 2023;18(10):e0293218
• All: 1 reference(s)