Secisbp2l^tm1.1Qiu
Targeted Allele Detail

Summary

• Symbol: Secisbp2l^tm1.1Qiu
• Name: SECIS binding protein 2-like; targeted mutation 1.1, Mengsheng Qiu
• MGI ID: MGI:7734969
• Synonyms: Secisbp2l^loxP
• Gene: Secisbp2l Location: Chr2:125578906-125624790 bp, - strand Genetic Position: Chr2, 61.76 cM
• Alliance: Secisbp2l^tm1.1Qiu page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:333465
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: An FRT-flanked neo cassette and loxP site were inserted upstream of exon 3 and a loxP site was inserted downstream of exon 3 via homologous recombination. Flp mediated recombination removed the neo cassette. (J:333465)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Secisbp2l Mutation: 73 strains or lines available

References

• Original: J:333465 Dai ZM, et al., SECISBP2L-Mediated Selenoprotein Synthesis Is Essential for Autonomous Regulation of Oligodendrocyte Differentiation. J Neurosci. 2022 Jul 27;42(30):5860-5869
• All: 1 reference(s)