Gmfg^tm1Jyw
Targeted Allele Detail

Summary

• Symbol: Gmfg^tm1Jyw
• Name: glia maturation factor, gamma; targeted mutation 1, Ji-Yang Wang
• MGI ID: MGI:7736707
• Gene: Gmfg Location: Chr7:28136894-28147655 bp, + strand Genetic Position: Chr7, 16.76 cM
• Alliance: Gmfg^tm1Jyw page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:345500
• Parent Cell Line: Bruce 4 (ES Cell)
• Strain of Origin: B6.Cg-Thy1^a

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Exons 1 - 4 were replaced with a floxed-neo cassette via homologous recombination. (J:345500)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gmfg Mutation: 18 strains or lines available

References

• Original: J:345500 Li Y, et al., Glia maturation factor-gamma is involved in S1P-induced marginal zone B-cell chemotaxis and optimal IgM production to type II T-independent antigen. Int Immunol. 2022 Jan 1;34(1):35-43
• All: 1 reference(s)