Snip1^M1Yiji
Chemically induced Allele Detail

Summary

• Symbol: Snip1^M1Yiji
• Name: Smad nuclear interacting protein 1; mutation 1, Yichang Jia
• MGI ID: MGI:7738213
• Synonyms: Snip^M
• Gene: Snip1 Location: Chr4:124960465-124967835 bp, + strand Genetic Position: Chr4, 57.99 cM
• Alliance: Snip1^M1Yiji page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Chemically induced (ENU) (Not Applicable)
• Mutation: Single point mutation
• Mutation details: This phenotypic allele was identified in a N-ethyl-N-nitrosourea (ENU) mutagenesis screen for dominant modifier(s) that rescue the Rnu2-8^{nmf291/nmf291} phenotypes. The molecular defect is a G to A substitution that alters the 5' splice site GT of exon 2 to AT. (J:354967)
• Inheritance: Dominant

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Snip1 Mutation: 19 strains or lines available

Notes

ENU mutagenesis was carried out in mice heterozygous for Rnu2-8^{nmf291/nmf291}.

References

• Original: J:354967 Meng D, et al., A molecular brake that modulates spliceosome pausing at detained introns contributes to neurodegeneration. Protein Cell. 2023 May 8;14(5):318-336
• All: 1 reference(s)