Snord118^em1Jfch
Endonuclease-mediated Allele Detail

Summary

• Symbol: Snord118^em1Jfch
• Name: small nucleolar RNA, C/D box 118; endonuclease-mediated mutation 1, Jian-Fu Chen
• MGI ID: MGI:7738727
• Synonyms: Snord118^f, Snord118 flox
• Gene: Snord118 Location: Chr11:68964253-68964387 bp, + strand Genetic Position: Chr11, 42.35 cM
• Alliance: Snord118^em1Jfch page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready)
• Mutation: Insertion
• The coding exon was flanked by loxP sites via CRISPR/Cas9 genome editing technology. (J:344970)

Expression

In Structures Affected by this Mutation:

7 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Snord118 Mutation: 0 strains or lines available

References

• Original: J:344970 Zhang W, et al., Recapitulating and reversing human brain ribosomopathy defects via the maladaptive integrated stress response. Sci Adv. 2024 Feb 2;10(5):eadk1034
• All: 1 reference(s)