Cox6b2^em1Osb
Endonuclease-mediated Allele Detail

Summary

• Symbol: Cox6b2^em1Osb
• Name: cytochrome c oxidase subunit 6B2; endonuclease-mediated mutation 1, Research Institute for Microbial Diseases, Osaka University
• MGI ID: MGI:7738839
• Synonyms: Cox6b2^-1171
• Gene: Cox6b2 Location: Chr7:4754791-4756093 bp, - strand Genetic Position: Chr7, 2.75 cM
• Alliance: Cox6b2^em1Osb page

Mutation origin

• Strain of Origin: (C57BL/6NJcl x DBA/2NJcl)F2

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR/Cas9 genome editing technology was used to generate a 1,171 bp deletion in the gene. (J:345850)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cox6b2 Mutation: 13 strains or lines available

References

• Original: J:345850 Shimada K, et al., Disruption of testis-enriched cytochrome c oxidase subunit COX6B2 but not COX8C leads to subfertility. Exp Anim. 2024 Feb 14;73(1):1-10
• All: 1 reference(s)