Cox8c^em1Osb
Endonuclease-mediated Allele Detail

Summary

• Symbol: Cox8c^em1Osb
• Name: cytochrome c oxidase subunit 8C; endonuclease-mediated mutation 1, Research Institute for Microbial Diseases, Osaka University
• MGI ID: MGI:7738840
• Synonyms: Cox8c^-988
• Gene: Cox8c Location: Chr12:102865575-102866785 bp, + strand Genetic Position: Chr12, 52.55 cM
• Alliance: Cox8c^em1Osb page

Mutation origin

• Strain of Origin: (C57BL/6NJcl x DBA/2NJcl)F2

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR/Cas9 genome editing technology was used to generate a 988 bp deletion in the gene. (J:345850)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cox8c Mutation: 8 strains or lines available

References

• Original: J:345850 Shimada K, et al., Disruption of testis-enriched cytochrome c oxidase subunit COX6B2 but not COX8C leads to subfertility. Exp Anim. 2024 Feb 14;73(1):1-10
• All: 1 reference(s)