Vsx2^{tm3.1(cre)Kash}
Targeted Allele Detail

Summary

• Symbol: Vsx2^{tm3.1(cre)Kash}
• Name: visual system homeobox 2; targeted mutation 3.1, Kamal Sharma
• MGI ID: MGI:7750853
• Synonyms: Chx10-cre, Chx10^cre, Chx10::Cre
• Gene: Vsx2 Location: Chr12:84616602-84642231 bp, + strand Genetic Position: Chr12, 39.28 cM
• Alliance: Vsx2^{tm3.1(cre)Kash} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:208772
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Recombinase)
• Mutation: Insertion
• Vsx2^{tm3.1(cre)Kash} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Vsx2 (MGI:88401)

• Mutation details: A targeting vector was designed to insert an open reading frame encoding Cre-recombinase followed by a polyA signal and an FRT-flanked neomycin cassette at the SacII restriction site upstream of the first exon position within the Vsx2 gene. The neo cassette was removed by germline deletion. (J:355222)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Vsx2 (mouse) Summary of all recombinase alleles driven by Vsx2. Alliance mouse Vsx2 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Vsx2 Mutation: 23 strains or lines available

References

• Original: J:208772 Azim E, et al., Skilled reaching relies on a V2a propriospinal internal copy circuit. Nature. 2014 Apr 17;508(7496):357-63
• All: 10 reference(s)