Tg(SAA)#Hiras
Transgene Detail

Summary

• Symbol: Tg(SAA)#Hiras
• Name: transgene insertion, Sachie Hiratsuka
• MGI ID: MGI:7764020
• Transgene: Tg(SAA)#Hiras Location: unknown
• Alliance: Tg(SAA)#Hiras page

Transgene origin

• Strain of Origin: C57BL/6J

Transgene description

• Transgene Type: Transgenic (Humanized sequence, Inserted expressed sequence)
• Mutation: Insertion
• Tg(SAA)#Hiras expresses 5 genes
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  SAA1 (6288)

  Saa1	(MGI:98221)
  Saa2	(MGI:98222)

  human

  SAA2 (6289)

  Saa1	(MGI:98221)
  Saa2	(MGI:98222)

  human

  SAA3P (6290)

  Saa3	(MGI:98223)

  human

  SAA4 (6291)

  Saa4	(MGI:98224)

  human

  SAAL1 (113174)

  Saal1

  (MGI:1926185)

• Mutation details: This transgene contains about 200 kb of BAC sequence containing human SAA cluster genes including; SAAL1, SAA3, SAA4, SAA2, and SAA1. Three lines were generated containing 1 - 3 copies of the BAC. This record represents pooled or unidentified lines. (J:355692)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:355692 Han Y, et al., Citrullinated fibrinogen-SAAs complex causes vascular metastagenesis. Nat Commun. 2023 Aug 24;14(1):4960
• All: 1 reference(s)