Prf1^{em3(cre/ERT2)Smoc}
Endonuclease-mediated Allele Detail

Summary

• Symbol: Prf1^{em3(cre/ERT2)Smoc}
• Name: perforin 1 (pore forming protein); endonuclease-mediated mutation 3, Shanghai Model Organisms Center
• MGI ID: MGI:7766543
• Synonyms: Prf1^{em1(IRES-CreERT2-WPRE-pA)Smoc}
• Gene: Prf1 Location: Chr10:61133612-61140459 bp, + strand Genetic Position: Chr10, 32.18 cM
• Alliance: Prf1^{em3(cre/ERT2)Smoc} page

Mutation origin

• Strain of Origin: C57BL/6JSmoc

Mutation description

• Allele Type: Endonuclease-mediated (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Prf1^{em3(cre/ERT2)Smoc} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Prf1 (MGI:97551)

• The IRES-CreERT2-WPRE-pA expression cassette was knocked into the gene stop codon site. (J:238766)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Prf1 (mouse) Summary of all recombinase alleles driven by Prf1. Alliance mouse Prf1 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Prf1 Mutation: 51 strains or lines available

References

• Original: J:238766 Shanghai Model Organisms Center, Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China. MGI Direct Data Submission. 2017
• All: 1 reference(s)