Draxin^m1
Spontaneous Allele Detail

Summary

• Symbol: Draxin^m1
• Name: dorsal inhibitory axon guidance protein; mutation 1
• MGI ID: MGI:7767935
• Gene: Draxin Location: Chr4:148182894-148215155 bp, - strand Genetic Position: Chr4, 78.67 cM, cytoband E1
• Alliance: Draxin^m1 page

Mutation origin

• Strain of Origin: BTBR T⁺ Itpr3^tf/J

Mutation description

• Allele Type: Spontaneous (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: An eight base-pair deletion introducing a premature stop codon in exon 2 was discovered in the BTBR T⁺ Itpr3^tf/J strain. (J:314104)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Draxin Mutation: 17 strains or lines available

References

• Original: J:314104 Morcom L, et al., DRAXIN regulates interhemispheric fissure remodelling to influence the extent of corpus callosum formation. Elife. 2021 May 4;10:e61618
• All: 1 reference(s)