Gigyf1^em1.1Xio
Endonuclease-mediated Allele Detail

Summary

• Symbol: Gigyf1^em1.1Xio
• Name: GRB10 interacting GYF protein 1; endonuclease-mediated mutation 1.1, Bo Xiong
• MGI ID: MGI:7779907
• Gene: Gigyf1 Location: Chr5:137516810-137526197 bp, + strand Genetic Position: Chr5, 76.53 cM
• Alliance: Gigyf1^em1.1Xio page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exons 10 to 24 were flanked by loxP sites via CRISPR/Cas9 technology. Cre-mediated recombination deleted exons 10-24. (J:335507)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gigyf1 Mutation: 28 strains or lines available

References

• Original: J:335507 Ding Z, et al., Genetic Ablation of GIGYF1, Associated With Autism, Causes Behavioral and Neurodevelopmental Defects in Zebrafish and Mice. Biol Psychiatry. 2023 Mar 15
• All: 1 reference(s)