Del(2Lcn8-Lcn10)10Osb
Endonuclease-mediated Allele Detail

Summary

• Symbol: Del(2Lcn8-Lcn10)10Osb
• Name: deletion, Chr 2, Research Institute for Microbial Diseases, Osaka University 10
• MGI ID: MGI:7780145
• Synonyms: (Lcn8-Lcn10)^del
• Gene: Del(2Lcn8-Lcn10)10Osb Location: unknown Genetic Position: Chr2, Syntenic

Mutation origin

• Strain of Origin: (C57BL/6NCrSlc x DBA/2CrSlc)F2

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intergenic deletion
• Del(2Lcn8-Lcn10)10Osb involves 4 genes/genome features (Lcn8, Lcn5, Lcn6 ...) View all
• Mutation details: CRISPR/Cas9 technology generated a 32521 bp deletion, deleting four lipocalin family genes, Lcn8, Lcn5, Lcn6, and Lcn10. (J:340906)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Del(2Lcn8-Lcn10)10Osb Mutation: 0 strains or lines available

References

• Original: J:340906 Sakurai N, et al., CRISPR/Cas9-mediated disruption of lipocalins, Ly6g5b, and Ly6g5c causes male subfertility in mice. Andrology. 2022 Nov 25
• All: 1 reference(s)