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Mir195bem1Dfra
Endonuclease-mediated Allele Detail
Summary
Symbol: Mir195bem1Dfra
Name: microRNA 195b; endonuclease-mediated mutation 1, Diego Franco
MGI ID: MGI:7781896
Synonyms: miR-195b-
Gene: Mir195b  Location: Chr2:56675823-56675919 bp, + strand  Genetic Position: Chr2, Syntenic
Alliance: Mir195bem1Dfra page
Mutation
origin
Strain of Origin:  C57BL/6 or CBA
Mutation
description
Allele Type:    Endonuclease-mediated (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsCRISPR/Cas9 technology generated a deletion encompassing the whole gene, including the premiRNA sequence. (J:344186)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Mir195b Mutation:  0 strains or lines available
References
Original:  J:344186 Munoz-Gallardo MDM, et al., miR-195b is required for proper cellular homeostasis in the elderly. Sci Rep. 2024 Jan 8;14(1):810
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory