Vaultrc5^em1.1Vdgl
Endonuclease-mediated Allele Detail

Summary

• Symbol: Vaultrc5^em1.1Vdgl
• Name: vault RNA component 5; endonuclease-mediated mutation 1.1, Joana A Vidigal
• MGI ID: MGI:7786417
• Gene: Vaultrc5 Location: Chr18:36934919-36935061 bp, + strand Genetic Position: Chr18, 19.46 cM
• Alliance: Vaultrc5^em1.1Vdgl page

Mutation origin

• Strain of Origin: C57BL/6NCr

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: CRISPR-targeting inserted loxP sites directly upstream and downstream from the annotated promoter and termination elements, respectively, without disrupting them. The entire vtRNA was deleted via cre-mediated recombination. (J:359009)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Vaultrc5 Mutation: 1 strain or line available

References

• Original: J:359009 Prajapat M, et al., The small noncoding RNA Vaultrc5 is dispensable to mouse development. RNA. 2024 Oct 16;30(11):1465-1476
• All: 1 reference(s)