Qrfpr^em1Smln
Endonuclease-mediated Allele Detail

Summary

• Symbol: Qrfpr^em1Smln
• Name: pyroglutamylated RFamide peptide receptor; endonuclease-mediated mutation 1, Simon M Luckman
• MGI ID: MGI:7788184
• Gene: Qrfpr Location: Chr3:36233575-36276462 bp, - strand Genetic Position: Chr3, 17.41 cM
• Alliance: Qrfpr^em1Smln page

Mutation origin

• Strain of Origin: C57BL/6NTac

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: CRISPR/Cas9 technology disrupted exon 1 and approximately 40 bp of the upstream proximal promoter sequence. (J:355747)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Qrfpr Mutation: 33 strains or lines available

References

• Original: J:355747 Cook C, et al., The hypothalamic RFamide, QRFP, increases feeding and locomotor activity: The role of Gpr103 and orexin receptors. PLoS One. 2022;17(10):e0275604
• All: 1 reference(s)