Pramel1^em2Liuw
Endonuclease-mediated Allele Detail

Summary

• Symbol: Pramel1^em2Liuw
• Name: PRAME like 1; endonuclease-mediated mutation 2, Wan-Sheng Liu
• MGI ID: MGI:7855637
• Gene: Pramel1 Location: Chr4:143120998-143126730 bp, + strand Genetic Position: Chr4, 77.64 cM
• Alliance: Pramel1^em2Liuw page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready)
• Mutation: Insertion
• CRISPR/cas9 mediated recombination introduced loxP sites flanking exons 2-4. (J:342835)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pramel1 Mutation: 21 strains or lines available

References

• Original: J:342835 Yang M, et al., Mouse Pramel1 regulates spermatogonial development by inhibiting retinoic acid signaling during spermatogenesis. Development. 2023 Nov 1;150(21):dev201907
• All: 1 reference(s)