Slc31a2^tm1.1Djt
Targeted Allele Detail

Summary

• Symbol: Slc31a2^tm1.1Djt
• Name: solute carrier family 31, member 2; targeted mutation 1.1, Dennis J Thiele
• MGI ID: MGI:7858957
• Gene: Slc31a2 Location: Chr4:62198630-62216649 bp, + strand Genetic Position: Chr4, 33.07 cM
• Alliance: Slc31a2^tm1.1Djt page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:202898
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A loxP site was inserted in intron 1 and a floxed pgk-neo cassette was inserted in intron 4 via homologous recombination. Cre-mediated recombination removed the neo cassette and exons 2-4. (J:202898)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Slc31a2 Mutation: 16 strains or lines available

References

• Original: J:202898 Ohrvik H, et al., Ctr2 regulates biogenesis of a cleaved form of mammalian Ctr1 metal transporter lacking the copper- and cisplatin-binding ecto-domain. Proc Natl Acad Sci U S A. 2013 Nov 12;110(46):E4279-88
• All: 2 reference(s)