Cnga3^em1Eye
Endonuclease-mediated Allele Detail

Summary

• Symbol: Cnga3^em1Eye
• Name: cyclic nucleotide gated channel alpha 3; endonuclease-mediated mutation 1, Stephen H Tsang
• MGI ID: MGI:7861929
• Synonyms: Cnga3^{floxed-miniSTOP}
• Gene: Cnga3 Location: Chr1:37257317-37302465 bp, + strand Genetic Position: Chr1, 15.46 cM, cytoband B
• Alliance: Cnga3^em1Eye page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready)
• Mutation: Insertion
• A floxed-miniSTOP cassette was inserted into intron 5 using Easi-CRISPR. (J:358897)

Disease models

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cnga3 Mutation: 27 strains or lines available

References

• Original: J:358897 Wang NK, et al., Mouse Models of Achromatopsia in Addressing Temporal "Point of No Return" in Gene-Therapy. Int J Mol Sci. 2021 Jul 28;22(15)
• All: 1 reference(s)