1700021F13Rik^em1Smoc
Endonuclease-mediated Allele Detail

Summary

• Symbol: 1700021F13Rik^em1Smoc
• Name: RIKEN cDNA 1700021F13 gene; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
• MGI ID: MGI:7865137
• Synonyms: LncCMRR^-, LncCMRR-KO
• Gene: 1700021F13Rik Location: Chr5:119943394-119945934 bp, - strand Genetic Position: Chr5, Syntenic
• Alliance: 1700021F13Rik^em1Smoc page

Mutation origin

• Strain of Origin: C57BL/6JSmoc

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: CRISPR-targeting of exon 3 generated a null allele. RT-qPCR analysis demonstrated a significant reduction of expression in the heart of 8-week-old homozygous mutant mice. (J:344873)
• Inheritance: Not Specified

Expression

In Mice Carrying this Mutation:	40 assay results
In Structures Affected by this Mutation:	2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any 1700021F13Rik Mutation: 0 strains or lines available

References

• Original: J:344873 Yang Y, et al., LncCMRR Plays an Important Role in Cardiac Differentiation by Regulating the Purb/Flk1 Axis. Stem Cells. 2023 Jan 30;41(1):11-25
• All: 1 reference(s)