Ermp1^em1Gjom
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ermp1^em1Gjom
• Name: endoplasmic reticulum metallopeptidase 1; endonuclease-mediated mutation 1, Monika Gjorgjieva
• MGI ID: MGI:7865790
• Gene: Ermp1 Location: Chr19:29587276-29625815 bp, - strand Genetic Position: Chr19, 24.17 cM
• Alliance: Ermp1^em1Gjom page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting of exon 1 generated a null allele. (J:361886)

Disease models

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ermp1 Mutation: 47 strains or lines available

References

• Original: J:361886 Correia de Sousa M, et al., ERMP1 as a newly identified endoplasmic reticulum stress gatekeeper in chronic kidney disease. Am J Physiol Renal Physiol. 2025;328(3):F375-F388
• All: 1 reference(s)