Wfdc15a^em1Ohbo
Endonuclease-mediated Allele Detail

Summary

• Symbol: Wfdc15a^em1Ohbo
• Name: WAP four-disulfide core domain 15A; endonuclease-mediated mutation 1, Kazuyuki Ohbo
• MGI ID: MGI:7868144
• Synonyms: Wfdc15a^-
• Gene: Wfdc15a Location: Chr2:164040783-164042050 bp, - strand Genetic Position: Chr2, 84.64 cM
• Alliance: Wfdc15a^em1Ohbo page

Mutation origin

• Strain of Origin: Slc:ICR

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Other
• Mutation details: CRISPR/Cas9 editing targeted to the protein-coding sequence of the first exon was used to generate a stop codon. (J:360881)

Expression

In Mice Carrying this Mutation:	3 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	5 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Wfdc15a Mutation: 9 strains or lines available

References

• Original: J:360881 Tomizawa SI, et al., The non-canonical bivalent gene Wfdc15a controls spermatogenic protease and immune homeostasis. Development. 2024 Sep 15;151(18):dev202834
• All: 1 reference(s)