Dclk3^tm1.1Geno
Targeted Allele Detail

Summary

• Symbol: Dclk3^tm1.1Geno
• Name: doublecortin-like kinase 3; targeted mutation 1.1, Genoway
• MGI ID: MGI:8158768
• Synonyms: Dclk3^flox
• Gene: Dclk3 Location: Chr9:111268149-111318186 bp, + strand Genetic Position: Chr9, 61.33 cM
• Alliance: Dclk3^tm1.1Geno page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:361634
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: A loxP site and FRT-flanked neomycin selection cassette was inserted upstream of the exon 2 and a second loxP site was inserted downstream of exon 2. The selection cassette was removed via flp-mediated recombination leaving exon 2 floxed. (J:361634)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Dclk3 Mutation: 42 strains or lines available

References

• Original: J:361634 de Longprez L, et al., Loss of the neuronal kinase DCLK3 leads to anxiety-like behaviour and memory deficits. Brain. 2025 Feb 5
• All: 1 reference(s)