Frrs1l^{tm1.1(FRRS1L)Jchoi}
Targeted Allele Detail

Summary

• Symbol: Frrs1l^{tm1.1(FRRS1L)Jchoi}
• Name: ferric-chelate reductase 1 like; targeted mutation 1, Jung Kyoon Choi
• MGI ID: MGI:8158797
• Synonyms: Frrs1l^h
• Gene: Frrs1l Location: Chr4:56957173-56990391 bp, - strand Genetic Position: Chr4, 31.66 cM
• Alliance: Frrs1l^{tm1.1(FRRS1L)Jchoi} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:361398
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Targeted (Humanized sequence, Inserted expressed sequence)
• Mutations: Insertion, Intragenic deletion
• Frrs1l^{tm1.1(FRRS1L)Jchoi} expresses 1 gene
  Knock-in expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  FRRS1L (23732)

  Frrs1l

  (MGI:2442704)

• Mutation details: The coding sequence of mouse exon 1 was replaced with human FRRS1L cDNA. The inserted FRT-flanked neomycin selection cassette was removed via flp-mediated recombination. Quantitative RT-PCR confirmed the expression of the human allele. (J:361398)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Frrs1l Mutation: 23 strains or lines available

References

• Original: J:361398 Lee KS, et al., Shared rare genetic variants in multiplex autism families suggest a social memory gene under selection. Sci Rep. 2025 Jan 3;15(1):696
• All: 1 reference(s)