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Tent5bem2Adki
Endonuclease-mediated Allele Detail
Summary
Symbol: Tent5bem2Adki
Name: terminal nucleotidyltransferase 5B; endonuclease-mediated mutation 2, Andrzej Dziembowski
MGI ID: MGI:8164232
Gene: Tent5b  Location: Chr4:133207443-133215249 bp, + strand  Genetic Position: Chr4, 66.25 cM
Alliance: Tent5bem2Adki page
Mutation
origin
Strain of Origin:  (C57BL/6JTar x CBA/WTar)F1
Mutation
description
Allele Type:    Endonuclease-mediated (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsCRISPR/Cas9 technology generated a deletion spanning the complete catalytic center of the protein, p.L121P; G122_S238del). (J:360869)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tent5b Mutation:  19 strains or lines available
References
Original:  J:360869 Brouze M, et al., TENT5-mediated polyadenylation of mRNAs encoding secreted proteins is essential for gametogenesis in mice. Nat Commun. 2024 Jun 22;15(1):5331
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory