Xaf1^em2.1Cya
Endonuclease-mediated Allele Detail

Summary

• Symbol: Xaf1^em2.1Cya
• Name: XIAP associated factor 1; endonuclease-mediated mutation 2.1, Cyagen Biosciences
• MGI ID: MGI:8164282
• Synonyms: Xaf1^-
• Gene: Xaf1 Location: Chr11:72192455-72204559 bp, + strand Genetic Position: Chr11, 43.99 cM
• Alliance: Xaf1^em2.1Cya page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Recombination removed exons 2 through 4. (J:344340)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Xaf1 Mutation: 18 strains or lines available

References

• Original: J:344340 Kuang M, et al., XAF1 promotes anti-RNA virus immune responses by regulating chromatin accessibility. Sci Adv. 2023 Aug 18;9(33):eadg5211
• All: 1 reference(s)