All Phenotypes A<w> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

A^w
white-bellied agouti
MGI:1855936

Summary

9 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	A^w/A^w	involves: SM/J	MGI:3789003
ht2	A^vy/A^w	129S1.C3-A^vy/A^w Chr 19^MOLF/Ei	MGI:3838979
ht3	A^y/A^w	129S1.C3-A^y/A^w Chr 19^MOLF/Ei	MGI:3838978
ht4	A^w/a	involves: SM/J	MGI:3789002
cx5	A^w/A^w As/As	involves: 101/H * C3H/HeH	MGI:4418714
cx6	A^w/a Corin^tm1Bamo/Corin^tm1Bamo	involves: 129X1/SvJ * C57BL/6 * FVB/N	MGI:3772887
cx7	A^w/A^w Corin^tm1Bamo/Corin^tm1Bamo	involves: 129X1/SvJ * C57BL/6 * FVB/N	MGI:3772888
cx8	A^w/a^t As/As⁺	Not Specified	MGI:4418722
ot9	A^w/?	Not Specified	MGI:3789009

Allelic Composition	A^w/A^w
Genetic Background	involves: SM/J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
A^w mutation (15 available); any a mutation (463 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

endocrine/exocrine glands

endocrine/exocrine gland phenotype ( J:19308 )

N	• total cortex and x-zone of adrenal cortex are of similar thickness to a/a, A^w/a, or A^w/ A^w 70-day old virgin mice • zona glomerulosa, zona fasciculata, and zona reticularis are morphologically similar between genotypes

abnormal adrenal gland x-zone morphology ( J:19308 )

• zone contains highly vacuolated cells

Allelic Composition	A^vy/A^w
Genetic Background	129S1.C3-A^vy/A^w Chr 19^MOLF/Ei

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
A^vy mutation (4 available); any a mutation (463 available)
A^w mutation (15 available); any a mutation (463 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

neoplasm

neoplasm ( J:146879 )

N	• mice exhibit the same incidence of testicular germ cell tumors as in 129S1/SvImJ-Chr 19/Na mice

Allelic Composition	A^y/A^w
Genetic Background	129S1.C3-A^y/A^w Chr 19^MOLF/Ei

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
A^w mutation (15 available); any a mutation (463 available)
A^y mutation (12 available); any a mutation (463 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

neoplasm

decreased incidence of induced tumors ( J:146879 )

• incidence of testicular germ cell tumors is decreased 24% compared to in 129S1/SvImJ-Chr 19/Na mice

growth/size/body

increased body weight ( J:146879 )

Allelic Composition	A^w/a
Genetic Background	involves: SM/J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
a mutation (229 available); any a mutation (463 available)
A^w mutation (15 available); any a mutation (463 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

endocrine/exocrine glands

endocrine/exocrine gland phenotype ( J:19308 )

N	• total cortex and x-zone of adrenal cortex are of similar thickness to a/a and A^w/ A^w 70-day old virgin mice • X-zone is composed exclusively of non-vacuolated cells • 70-day old hybrids of mixed C57BL/6 and SM/J background have non-vacuolated x-zones

Allelic Composition	A^w/A^w As/As
Genetic Background	involves: 101/H * C3H/HeH

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
As mutation (0 available); any As mutation (0 available)
A^w mutation (15 available); any a mutation (463 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

pigmentation

abnormal coat/hair pigmentation ( J:5027 )

darkened coat color ( J:5027 )

• the top of the head is nearly non-agouti

• the size of the yellow band and percentage of banded hairs are reduced darkening the over-all coat

• the belly is dark agouti rather than the expected white or cream color

integument

abnormal coat/hair pigmentation ( J:5027 )

darkened coat color ( J:5027 )

• the size of the yellow band and percentage of banded hairs are reduced darkening the over-all coat

• the top of the head is nearly non-agouti

• the belly is dark agouti rather than the expected white or cream color

Allelic Composition	A^w/a Corin^tm1Bamo/Corin^tm1Bamo
Genetic Background	involves: 129X1/SvJ * C57BL/6 * FVB/N

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
a mutation (229 available); any a mutation (463 available)
A^w mutation (15 available); any a mutation (463 available)
Corin^tm1Bamo mutation (0 available); any Corin mutation (68 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

pigmentation

diluted coat color ( J:130426 )

• mice exhibit a progressively lighter coat color with additional functioning non-agouti allele

• Background Sensitivity: authors state that mice on a 129 or FVB background for more than 6 generation exhibit a qualitatively similar phenotype

integument

diluted coat color ( J:130426 )

• mice exhibit a progressively lighter coat color with additional functioning non-agouti allele

• Background Sensitivity: authors state that mice on a 129 or FVB background for more than 6 generation exhibit a qualitatively similar phenotype

Allelic Composition	A^w/A^w Corin^tm1Bamo/Corin^tm1Bamo
Genetic Background	involves: 129X1/SvJ * C57BL/6 * FVB/N

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
A^w mutation (15 available); any a mutation (463 available)
Corin^tm1Bamo mutation (0 available); any Corin mutation (68 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

pigmentation

diluted coat color ( J:130426 )

• mice exhibit a progressively lighter coat color with additional functioning non-agouti allele

• Background Sensitivity: authors state that mice on a 129 or FVB background for more than 6 generation exhibit a qualitatively similar phenotype

integument

diluted coat color ( J:130426 )

• mice exhibit a progressively lighter coat color with additional functioning non-agouti allele

• Background Sensitivity: authors state that mice on a 129 or FVB background for more than 6 generation exhibit a qualitatively similar phenotype

Allelic Composition	A^w/a^t As/As⁺
Genetic Background	Not Specified

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
As mutation (0 available); any As mutation (0 available)
a^t mutation (9 available); any a mutation (463 available)
A^w mutation (15 available); any a mutation (463 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

pigmentation

abnormal coat/hair pigmentation ( J:5027 )

• this allele only affects the agouti allele present on the same chromosome

• this genotype results in normal light-bellied agouti; not the anticipated cream color from the a^t allele and seen in a mouse genotype AsA^w/As<+>a^t

integument

abnormal coat/hair pigmentation ( J:5027 )

• this allele only affects the agouti allele present on the same chromosome

• this genotype results in normal light-bellied agouti; not the anticipated cream color from the a^t allele and seen in a mouse genotype AsA^w/As<+>a^t

Allelic Composition	A^w/?
Genetic Background	Not Specified

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
A^w mutation (15 available); any a mutation (463 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

pigmentation

yellow coat color ( J:22600 )

• hairs on back have narrow yellow band near the tip; belly hairs are light yellow for most of their length

• coat is lighter in general than normal agouti coat

abnormal ventral coat pigmentation ( J:22600 , J:78801 )

• belly of animal is white, cream, or tan (yellow) in color; hairs originating on ventrum may be frequently nonpigmented, possess yellow pigment or are predominantly yellow with black bases compared to A/A mice (J:78801)

• A^w is dominant to A and all lower alleles (J:78801)

integument

yellow coat color ( J:22600 )

• hairs on back have narrow yellow band near the tip; belly hairs are light yellow for most of their length

• coat is lighter in general than normal agouti coat

abnormal ventral coat pigmentation ( J:22600 , J:78801 )

• A^w is dominant to A and all lower alleles (J:78801)

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