pigmentation
• tyrosinase levels in 7 day regenerating hairbulb melanocytes, as determined by immunotitration, are reduced in comparison to a/a controls, however, levels increase in 10 day regenerating hairbulbs, although not to control levels, suggesting a switch to melanin (black/brown) synthesis
• decreased tyrosinase in 7 day regenerating hairbulbs suggests the production of predominantly phaeomelanin (yellow)
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• light belly resembles Aw
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homeostasis/metabolism
• mice exhibit lower levels of melanocyte stimulating hormone in sera, whole pituitary and 5, 7, and 9 day regenerating hair bulbs than a/a and Ay mice
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integument
• tyrosinase levels in 7 day regenerating hairbulb melanocytes, as determined by immunotitration, are reduced in comparison to a/a controls, however, levels increase in 10 day regenerating hairbulbs, although not to control levels, suggesting a switch to melanin (black/brown) synthesis
• decreased tyrosinase in 7 day regenerating hairbulbs suggests the production of predominantly phaeomelanin (yellow)
|
• light belly resembles Aw
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