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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Aw-J
white bellied agouti Jackson
MGI:1855946
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Aw-J/Aw-J C57BL/6J-Aw-J/J MGI:3802742


Genotype
MGI:3802742
hm1
Allelic
Composition
Aw-J/Aw-J
Genetic
Background
C57BL/6J-Aw-J/J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Aw-J mutation (28 available); any a mutation (463 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
pigmentation
• tyrosinase levels in 7 day regenerating hairbulb melanocytes, as determined by immunotitration, are reduced in comparison to a/a controls, however, levels increase in 10 day regenerating hairbulbs, although not to control levels, suggesting a switch to melanin (black/brown) synthesis
• decreased tyrosinase in 7 day regenerating hairbulbs suggests the production of predominantly phaeomelanin (yellow)
• light belly resembles Aw

homeostasis/metabolism
• mice exhibit lower levels of melanocyte stimulating hormone in sera, whole pituitary and 5, 7, and 9 day regenerating hair bulbs than a/a and Ay mice

integument
• tyrosinase levels in 7 day regenerating hairbulb melanocytes, as determined by immunotitration, are reduced in comparison to a/a controls, however, levels increase in 10 day regenerating hairbulbs, although not to control levels, suggesting a switch to melanin (black/brown) synthesis
• decreased tyrosinase in 7 day regenerating hairbulbs suggests the production of predominantly phaeomelanin (yellow)
• light belly resembles Aw





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory