Phenotypes associated with this allele

• Allele Symbol: Acan^cmd-Bc
• Allele Name: cartilage matrix deficiency British Columbia
• Allele ID: MGI:1855999
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Acan^cmd-Bc/Acan^cmd-Bc	BALB/cGaBc-Acan^cmd-Bc	MGI:4354140

Genotype
MGI:4354140

hm1

• Allelic Composition: Acan^cmd-Bc/Acan^cmd-Bc
• Genetic Background: BALB/cGaBc-Acan^cmd-Bc

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

neonatal lethality, complete penetrance ( J:65316 )

• homozygotes die at birth due to asphyxiation

respiratory system

pulmonary hypoplasia ( J:65316 )

respiratory failure ( J:65316 )

craniofacial

cleft palate ( J:58755 )

protruding tongue ( J:58755 )

• the tongue protrudes due to cleft palate

short snout ( J:58755 )

digestive/alimentary system

cleft palate ( J:58755 )

protruding tongue ( J:58755 )

• the tongue protrudes due to cleft palate

limbs/digits/tail

abnormal limb development ( J:58755 )

• both reduced limb length and abnormal limb shape are detected as early as E15

short limbs ( J:65316 )

growth/size/body

cleft palate ( J:58755 )

protruding tongue ( J:58755 )

• the tongue protrudes due to cleft palate

short snout ( J:58755 )

small thoracic cavity ( J:65316 )

• severely reduced thoracic cavity

distended abdomen ( J:58755 )