Phenotypes associated with this allele

• Allele Symbol: Hephl1^cw-thd
• Allele Name: tail hair depletion
• Allele ID: MGI:1856003
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Hephl1^cw-thd/Hephl1^cw-thd	SJL/J	MGI:3590084

Genotype
MGI:3590084

hm1

• Allelic Composition: Hephl1^cw-thd/Hephl1^cw-thd
• Genetic Background: SJL/J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

immune system

abnormal humoral immune response ( J:15004 )

• mice show, by tail skin graft rejection, an uncharacteristic response to certain polysaccharide antigens

• mutant mice accept tail skin grafts from normal mice; but normal mice reject tail skin grafts from mutant mice over a 12 week period

• mice still show expected incidence and latent period of the SJL/J Hodgkin's-like lesion

• response to sheep red blood cells is normal

integument

focal hair loss ( J:15004 )

• hair is noticeably depleted on the tail by 2 weeks of age and also on the feet, genitals, and around nipples

abnormal vibrissa morphology ( J:15004 )

sparse vibrissae ( J:15004 )

• observable by 2 weeks of age

wavy vibrissae ( J:15004 )

• observable by 2 weeks of age